EFFECT OF SODIUM NITROPRUSSIDE-INDUCED HYPOTENSION ON PULMONARY DEADSPACE
نویسندگان
چکیده
منابع مشابه
Effect of sodium nitroprusside-induced hypotension on pulmonary deadspace.
Deliberate hypotension with nitroprusside produced a 40% reduction in mean arterial pressure, but it did not cause any change in the pulmonary deadspace to tidal volume ratio ( Vb/ Vr). This was achieved by adequate hydration both before and during hypotension, as indicated by constant filling pressures. Thus we have shown that deliberate hypotension per se does not increase Vb/ VT, and that va...
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In seven dogs anaesthetized with pentobarbitone, coronary and pulmonary artery blood flows were measured using electromagnetic flow meters. The infusion of a 0.01% solution of sodium nitroprusside caused an initial small increase in mean coronary artery flow which returned to control as the arterial pressure decreased. No changes were noted in cardiac output nor were further changes observed in...
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Orthostatic hypotension is most common in elderly people, and its prevalence increases with age. Attenuation of the vestibulo-sympathetic reflex (VSR) is commonly associated with orthostatic hypotension. In this study, we investigated the role of glutamate on the vestibulo-solitary projection of the VSR pathway to clarify the pathophysiology of orthostatic hypotension. Blood pressure and expres...
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In two groups of patients undergoing induced hypotension with sodium nitroprusside or trimetaphan blood concentrations of lactate, pyruvate and standard bicarbonate did not differ significantly between the groups. In the nine patients who received trimetaphan there was a progressive, but statistically non-significant, decrease in mean lactate. Nitroprusside (15 patients) was associated with a s...
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Several recently reported deaths following the use of sodium nitroprusside have been attributed to the accumulation of the nitroprusside metabolite, cyanide. In this study, brief nitroprusside infusions (mean = 36 minutes) were administered in currently recommended doses during intracranial surgery. The peak blood cyanide following the infusions was 65.2 +/- 17.5 microgram per cent (mean +/- SE...
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ژورنال
عنوان ژورنال: British Journal of Anaesthesia
سال: 1982
ISSN: 0007-0912
DOI: 10.1093/bja/54.11.1197